Nodular Regenerative Hyperplasia in HIV-positive patients : a case series and review of the literature
| Journal | Volume 80 - 2017 |
| Issue | Fasc.1 - Original articles |
| Author(s) | M. Figueiredo, M. Nkuize, JP Mulkay, S. De Wit, M. Gomez, T. Sersté |
| Full article |
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| (1) Department of Hepatogastroenterology, UMC Saint Pierre, Université Libre de Bruxelles, Brussels, Belgium ; (2) Department of Infectious Diseases, UMC Saint Pierre, Université Libre de Bruxelles, Brussels, Belgium ; (3) Department of Histology and Pathology, Juled Bordet Institute, Université Libre de Bruxelles, Brussels, Belgium ; (4) Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, C.U.B. Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. |
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Nodular regenerative hyperplasia (NRH) is a well-described condition that leads to non-cirrhotic portal hypertension and is histologically characterised by a nodular transformation of the liver without fibrosis. It seems to be a consequence of obliterative portal venopathy of small hepatic veins. Its precise aetiology remains to be clearly determined. NRH was reported to occur in HIV-positive patients ten years ago. In this article, three consecutive clinical cases of HIV-related NRH were identified in a high volume reference centre of HIV positive patients and are presented. Clinical, diagnostic aspects and strategies for management of this under-diagnosed medical condition in the HIV population are also developed. (Acta gastroenterol. belg., 2017, 80, 15-19). |
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© Acta Gastro-Enterologica Belgica. PMID 29364092 |
